Project leaders |
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Dr. Dominik Meidner, Technische Universität München, Germany |
Prof. Dr. Thomas Richter ![]() |
Prof. Dr. Stefan Turek ![]() |
Prof. Dr. Boris Vexler, Technische Universität München, Germany |
Dr. Vladimir Matoussevitch ![]() |
Project staff |
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Dr. Lukas Failer, Technische Universität München, Deutschland |
Dr. Abderrahim Ouazzi ![]() |
Dr. Piotr Minakowski ![]() |
Project partner |
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abmedica Deutschland ![]() |
Spectranetics Deutschland ![]() |
C. R.Bard ![]() |
Project description |
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The aim of the research project is the development of efficient numerical methods to model, simulate and control the complex flow behavior in blood vessels considering active material change, damage, and growth. Thereby we analyze the hemodynamical effects of the challenging prototypical and very complex example of an arterial shunt of the arteria brachialis and the vena cephalica to prepare dialysis treatment. The procedure extremely changes the flow behavior in the blood vessels and increases the flow rate up to 10 times. The result of all this can be the damage of the vessel or the development of a sentosis. The focus of the project will be on the vena cephalic, and the development and treatment of the the cephalic arch stenosis(CAS), which occurrence depends on patient specific situation. Together with the industrial partners ab medica, Spetranetics and C.R. Bard the primal goal of the project is the development of personalized products using patient specific simulations. We analyze techniques to control the flow, for example through a stent to encourage a positive development of the disease. |
Key words |
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fluid-strukture interaction, optimal control, blood flow |
Field of work |
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Applied Mathematics, Numerical Mathematics und inverse problems |
Publications |
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• | Lukas Failer, Thomas Wick: Adaptive Time-Step Control for Nonlinear Fluid-Structure Interaction Journal of Computational Physics, 2018. (doi:10.1016/j.jcp.2018.04.021) |
• | Lukas Failer, Dominik Meidner, Boris Vexler: Optimal Control of a Linear Unsteady Fluid-Structure Interaction Problem Journal of Optimization Theory and Applications, 170(1), pp. 1-27, 2016. (doi:10.1007/s10957-016-0930-1) |
Conferences |
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International Symposium on Simulation and Optimization of Extreme Fluids ![]() |
Winter School on Simulation and Optimization of Extreme Fluids ![]() |
Software |
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Gascoigne, RoDoBo |